APA Annual Meeting 2022 On-Demand Package-NIDA Clinical Trial Network: Research Updates and Future Directions in the Treatment of Methamphetamine User Disorder

NIDA Clinical Trial Network: Research Updates and Future Directions in the Treatment of Methamphetamine User Disorder

Video Transcription

Video Summary

Video Summary:<br /><br />The first video discusses research updates and future directions in the treatment of methamphetamine use disorder. The speaker emphasizes the need for effective interventions to address the increase in methamphetamine use and overdose deaths. They highlight ongoing research efforts, including a study on the combination of naltrexone and bupropion, which showed promising results. The use of transcranial magnetic stimulation (TMS) to target the dorsolateral prefrontal cortex is also mentioned. The video concludes by discussing ongoing research on the use of ketamine for methamphetamine use disorder treatment.<br /><br />The second video focuses on the use of ketamine and other medications in the treatment of depression, substance use disorders, and specifically methamphetamine use disorder. Studies have shown that ketamine rapidly improves depression symptoms, with repeated dosing maintaining the improvement. Intranasal esketamine has shown mixed results for treatment-resistant depression, but long-term use has sustained improvement. Ketamine has also shown positive results in reducing drug use for cocaine dependence and alcohol use disorder. Ongoing research is being conducted to evaluate the efficacy of ketamine for methamphetamine use disorder, with the aim of sustained improvement in abstinence. The video highlights the importance of targeting glutamate neurotransmission and the need for further research on the use of ketamine and other medications for substance use disorders.<br /><br />Overall, both videos highlight the increasing need for effective interventions for methamphetamine use disorder and provide updates on ongoing research efforts, particularly focusing on the potential of ketamine and other medications in treatment.

Keywords

methamphetamine use disorder

research updates

interventions

methamphetamine use

overdose deaths

naltrexone

bupropion

transcranial magnetic stimulation

ketamine

depression

substance use disorders

glutamate neurotransmission