Objective: Postpartum psychiatric disorders are common and morbid complications of pregnancy. The authors sought to evaluate how family history of psychiatric disorders is associated with postpartum psychiatric disorders in proband mothers with and without a prior psychiatric history by assessing degree of relationship, type of disorder, and sex of family members.
Method: The authors linked Danish birth and psychiatric treatment registers to evaluate familial risk of postpartum psychiatric episodes in a national population-based cohort. Probands were first-time mothers who were born in Denmark in 1970 or later and who gave birth after age 15 and before Dec. 31, 2012 (N=362,462). The primary exposure was a diagnosed psychiatric disorder in a relative. Cox regression models were used to estimate the hazard ratio of postpartum psychiatric disorders in proband mothers.
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The participant will distinguish the role of family psychiatric history and other risk factors for predicting postpartum psychiatric disorders.
This program is designed for all psychiatrists in clinical practice, residents in Graduate Medical Education programs, medical students interested in psychiatry, and other physicians who wish to advance their current knowledge of clinical medicine.
Duration: 1 hour
Begin Date: August 1, 2018
End Date: July 31, 2020
In order to earn CME credit, subscribers should read through the material presented in the article. After reading the article, complete the quiz and submit your evaluation and study hours (up to 1 AMA PRA Category 1 Credit™). A score of 60% or higher is required to receive credit.
The American Psychiatric Association (APA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
The APA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Title: Familiality of Psychiatric Disorders and Risk of Postpartum Psychiatric Episodes: A Population-Based Cohort Study
Authors: Anna E. Bauer, Ph.D., Merete L. Maegbaek, M.Sc., Xiaoqin Liu, Ph.D., Naomi R. Wray, Ph.D., Patrick F. Sullivan, M.D., F.R.A.N.Z.C.P., William C. Miller, M.D., Samantha Meltzer-Brody, M.D., Trine Munk-Olsen, Ph.D.
Affiliations: From the Departments of Psychiatry and Genetics, University of North Carolina at Chapel Hill (A.E.B., P.F.S., S.M.-B.); the National Center for Register-Based Research, Aarhus University, Aarhus, Denmark (M.L.M., X.L., T.M.-O.); the Institute for Molecular Bioscience and Queensland Brain Institute, University of Queensland, Brisbane, Australia (N.R.W.); and the Ohio State University College of Public Health, Columbus (W.C.M.).
Disclosures: Dr. Wray has received funding from the Australian National Health and Medical Research Council (grants 1078901 and 1087889). Dr. Sullivan has received grant support from Lundbeck and has served on advisory boards or as a consultant or speaker for Element Genomics, Lundbeck, Pfizer, and Roche. Dr. Meltzer-Brody has received research grant support from Janssen and Sage Therapeutics. Dr. Munk-Olsen is supported by the Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) (grant R155-2014-1724). The other authors report no financial relationships with commercial interests.
Discussion of unapproved or investigational use of products*: No.
*APA policy requires disclosure by CME authors of unapproved or investigational use of products discussed in CME programs. Off-label use of medications by individual physicians is permitted and common. Decisions about off-label use can be guided by scientific literature and clinical experience.
Robert Freedman, M.D. (Editor-in-Chief, AJP); Susan K. Schultz, M.D. (Deputy Editor, AJP); Michael D. Roy (Editorial Director, AJP); Michael A. Pogachar (Online Content Manager, Journals).
Dr. Schultz has received research support from the Alzheimer’s Disease Cooperative Study for projects conducted in partnership with Toyama Chemical Company and in partnership with Eli Lilly and Company. Dr. Freedman, Mr. Roy, and Mr. Pogachar report no financial relationships with commercial interests.
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