Children of parents with major depression (MDD) are at significantly increased risk for developing major depression themselves; however, not all children at genetic risk will develop MDD. We investigated the utility of subsyndromal scores on the Child Behavior Checklist (CBCL) Anxiety/Depression scale in identifying children at the highest risk for pediatric MDD from among the pool of children of parents with MDD or bipolar disorder. Subsyndromal scores on the CBCL Anxiety/Depression scale significantly separated the children at high risk for pediatric MDD from those at low risk in a variety of functional areas, including social and academic functioning. Additionally, children at genetic risk without elevated CBCL Anxiety/Depression scale scores were largely indistinguishable from controls. These results suggest that the CBCL Anxiety/Depression scale can help identify children at highest risk for pediatric MDD. If implemented clinically, this scale would cost-effectively screen children and identify those most in need of early intervention resources to impede the progression of depression. This presentation provides an overview of major depression in children and articulates the use of the Child Behavior Checklist (CBCL) to identify children at greater risk for depression.
**This content was captured at the 2017 APA Annual Meeting and may reference information from various sources and terminology from previous editions of the DSM.
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- Differentiate between pediatric major depression and subsyndromal depression
- Describe the utility of subsyndromal scores on the Child Behavior Checklist (CBCL) scale
- Discuss the clinical significance for identifying a child or adolescent with subsyndromal depression
Estimated Time to Complete
Estimated Duration: 15 minutes
Begin Date: Octber 1, 2018
End Date: December 31, 2020
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Faculty and Planner Disclosures
- Kenny Lin, M.D., Massachusetts General Hospital. Reports no financial relationships with commercial interests.
- Tristan Gorrindo, M.D., Director of Education, American Psychiatric Association. Reports no financial relationships with commercial interests.
- Ricardo A. Juarez, M.S., Director, District Branch and International Relations, American Psychiatric Association. Reports no financial relationships with commercial interests.
- Luciana Giambarberi, M.D., Wake Forest School of Medicine. Reports no financial relationships with commercial interests.
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