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Main Results and Clinical Implications of the X:BOT Trial: XR-Naltrexone vs. Buprenorphine-Naloxone Film

Activity Type:

  • On Demand


Release Date: 7/31/2018

Expiration Date: 7/31/2021

  • AMA PRA Category 1 Physician: 1
  • Participation: 1

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Overview

There is nearly a half century of overwhelming evidence that agonist substitution, initially with methadone and more recently with buprenorphine and naltrexone, is both efficacious in clinical trials and effective in the community in promoting and sustaining abstinence and reducing risks associated with opioid dependence

This webinar will examine the largest such evaluation to date of extended-release naltrexone (XR-NTX) opioid treatment compared to a gold standard of care, buprenorphine maintenance, and discuss the relevance of the data to clinical practice. 

Pricing

  • General Member - Free
  • Resident-Fellow Member - Free
  • Medical Student Member - Free
  • Non-Member - Free

Educational Objectives

  • Describe the aims and methods of the X:BOT trial.
  • Compare XR-NTX vs. BUP-NX effects on relapse-free survival, opioid use rates, and overdose events.

Target Audience

Physicians who have a waiver to treat opioid use disorder in an office-based setting and other interested clinicians.

Estimated Time to Complete

Estimated Duration: 1 hour
Begin Date: July 31, 2018
End Date: July 31, 2021

How to Earn Credit

Participants who wish to earn AMA PRA Category 1 Credit™ or a certificate of participation may do so by completing all sections of the course including the evaluation. A multiple-choice quiz is provided based on the content. A passing score of 100% must be achieved. Retakes are available for the test. After evaluating the program, course participants will be provided with an opportunity to claim hours of participation and print an official CME certificate (physicians) or certificate of participation (non-physicians) showing the completion date and hours earned. 

Accreditation

The American Psychiatric Association (APA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The APA designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Faculty and Planner Disclosures

Faculty

  • Joshua D. Lee, M.D., NYU Langone Health, Reports no finanical relationships with commercial interests

Program Planners

  • John A. Renner, Jr., M.D., Boston University School of Medicine, Director, Addiction Psychiatry Residency Training, Boston University Medical Center and VA Boston Healthcare System. Disclosure: Stockholder: Johnson & Johnson and General Electric. 
  • Eunice Maize,  American Psychiatric Association. Reports no finanical relationships with commercial interests
  • Tristan Gorrindo,M.D.,  American Psychiatric Association, Reports no finanical relationships with commercial interests 

Hardware/Software Requirements

This internet-based CME activity is best experienced using Internet Explorer 8+, Mozilla Firefox 3+, Safari 4+. This Web site requires that JavaScript and session cookies be enabled. Certain activities may require additional software to view multimedia, presentation, or printable versions of the content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Adobe Acrobat, Microsoft PowerPoint, and Windows Media Player.

Optimal System Configuration:

  • Flash Player: Adobe Flash Player 10.3+ 
  • Browser: Firefox (latest version), Internet Explorer 8.0+, Safari 7.0+, Microsoft Edge (latest version) or Google Chrome (latest version)
  • Operating System: Windows XP+ or Mac OS X 10.4+ 
  • Internet Connection: 1 Mbps or higher

Minimum Requirements:

  • Windows PC: 500-MHz Pentium II; Windows XP or higher; 128 MB RAM; Video Card at least 64MB of video memory; Macromedia Flash Player 10.3 or higher; Sound Card at least 16-bit; audio playback with speakers for programs with video content
  • Macintosh:Mac OS X 10.4+ or higher with latest updates installed; 1.83MHz Intel Core Duo or faster; RAM: 128MB or more; Video Card: at least 64MB of video memory; Sound Card: at least 16-bit; audio playback with speakers for programs with video content

For assistance: Contact pcssmat@psych.org for questions about this course | Contact learningcenter@psych.org for technical assistance

All materials copyright American Psychiatric Association. ©2018

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