Activity Preview


AJP CME: October 2016 - Offspring of Depressed Parents: 30 Years Later

Activity Type:

  • Journal CME

Release Date: 10/1/2016

Expiration Date: 9/30/2018

  • AMA PRA Category 1 Physician: 1
  • Participation: 1

Access Activity


Objective: While the increased risk of psychopathology in the biological offspring of depressed parents has been widely replicated, the long-term outcome through their full age of risk is less known. The authors present a 30-year follow-up of biological offspring (mean age=47 years) of depressed (high-risk) and nondepressed (low-risk) parents.

Method: One hundred forty-seven offspring of moderately to severely depressed or nondepressed parents selected from the same community were followed for up to 30 years. Diagnostic assessments were conducted blind to parents’ clinical status. Final diagnoses were made by a blinded M.D. or Ph.D. evaluator.

Subscription and Pricing

This activity is only available to AJP CME subscribers.

Don't have a subscription to AJP CME? Subscribe Now! 

  • AJP Subscriber – 12 Month CME Subscription: $150.00
  • Non AJP Subscriber – 12 Month CME Subscription: $300.00

If you have questions about AJP CME subscriptions, please contact

Educational Objective

The participant will distinguish key differences in measures of depression, morbidity, and mortality between offspring of parents with and without depression who were followed for 30 years.

Target Audience

This program is designed for all psychiatrists in clinical practice, residents in Graduate Medical Education programs, medical students interested in psychiatry, and other physicians who wish to advance their current knowledge of clinical medicine.

Estimated Time to Complete

Duration: 1 hour
Begin Date: October 1, 2016
End Date: September 30, 2018

How to Earn Credit

In order to earn CME credit, subscribers should read through the material presented in the article. After reading the article, complete the quiz and submit your evaluation and study hours (up to 1 AMA PRA Category 1 Credit™).  A score of 60% or higher is required to receive credit.


The American Psychiatric Association (APA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The APA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Faculty and Planner Disclosures

Title: Offspring of Depressed Parents: 30 Years Later

Authors: Myrna M. Weissman, Ph.D., Priya Wickramaratne, Ph.D., Marc J. Gameroff, Ph.D., Virginia Warner, Dr.P.H., Daniel Pilowsky, M.D., M.P.H., Rajni Gathibandhe Kohad, M.D, M.P.H., Helena Verdeli, Ph.D., Jamie Skipper, M.A., Ardesheer Talati, Ph.D.

Affiliations: From the Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York (M.M.W., P.W., M.J.G., V.W., D.P., A.T.); the Mailman School of Public Health, Columbia University, New York (M.M.W., P.W., D.P.); the Division of Epidemiology, New York State Psychiatric Institute, New York (M.M.W., P.W., M.J.G., V.W., D.P., R.G.K., H.V., J.S., A.T.); and Teachers College, Columbia University, New York (H.V.).

Disclosures: Dr. Weissman has received funding from the National Institute on Drug Abuse, NARSAD, NIMH, the Sackler Foundation, and the Templeton Foundation; she also receives royalties from American Psychiatric Association Publishing, Multihealth Systems, Perseus Press, and Oxford University Press. Dr. Verdeli has received honoraria for psychotherapy training (Navy mental health staff and residents, Navy Medical Center Portsmouth; Fordham Institute for Humanitarian Studies [Ethiopia]; and StrongMinds [NGO, Uganda]) and for serving as keynote speaker at the Annual Meeting of the Society for Psychotherapy in Primary Care, University of Bologna, 2014; she has served as reviewer of psychotherapy supervision procedures for the World Bank Manual (Johns Hopkins University Press); she has received research funding from the International Medical Corps (NGO), as well as from Grand Challenges Canada; and she serves as Associate Editor of Global Mental Health. All other authors report no financial relationships with commercial interests.

Discussion of unapproved or investigational use of products*: No.

*APA policy requires disclosure by CME authors of unapproved or investigational use of products discussed in CME programs. Off-label use of medications by individual physicians is permitted and common. Decisions about off-label use can be guided by scientific literature and clinical experience.

Program Planners

Robert Freedman, M.D. (Editor-in-Chief, AJP); Susan K. Schultz, M.D. (Deputy Editor, AJP); Michael D. Roy (Editorial Director, AJP) ; Michael A. Pogachar (Online Content Manager, Journals).

Dr. Schultz has received research support from the Alzheimer’s Disease Cooperative Study for projects conducted in partnership with Toyama Chemical Company and in partnership with Eli Lilly and Company. Dr. Freedman, Mr. Roy, and Mr. Pogachar report no financial relationships with commercial interests.

Hardware/Software Requirements

This internet-based CME activity is best experienced using Internet Explorer 8+, Mozilla Firefox 3+, Safari 4+. This Web site requires that JavaScript and session cookies be enabled. Certain activities may require additional software to view multimedia, presentation, or printable versions of the content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Adobe Acrobat, Microsoft PowerPoint, and Windows Media Player.

Optimal System Configuration:

  • Flash Player: Adobe Flash Player 10.3+ 
  • Browser: Firefox (latest version), Internet Explorer 8.0+, Safari 7.0+, Microsoft Edge (latest version) or Google Chrome (latest version)
  • Operating System: Windows XP+ or Mac OS X 10.4+ 
  • Internet Connection: 1 Mbps or higher

Minimum Requirements:

  • Windows PC: 500-MHz Pentium II; Windows XP or higher; 128 MB RAM; Video Card at least 64MB of video memory; Macromedia Flash Player 10.3 or higher; Sound Card at least 16-bit; audio playback with speakers for programs with video content
  • Macintosh:Mac OS X 10.4+ or higher with latest updates installed; 1.83MHz Intel Core Duo or faster; RAM: 128MB or more; Video Card: at least 64MB of video memory; Sound Card: at least 16-bit; audio playback with speakers for programs with video content

For assistance: Contact for questions about this course | Contact for technical assistance

Access Activity