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Using Clozapine: Public and Academic Approaches to Full Recovery

Activity Type:

  • On Demand

Release Date: 8/20/2015

Expiration Date: 8/20/2018

  • AMA PRA Category 1: 1
  • Participation: 1

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Clozapine's underutilization is the quintessential science-to-service gap in behavioral health services. Long-recognized as the most efficacious medication for treatment-refractory schizophrenia, clozapine has gained the unfortunate reputation of being difficult to tolerate, prescribe, and disseminate as an evidence-based practice for consumers, prescribers, and advocates alike. Moreover, there are clinical and geographic disparities in the use of clozapine nationally and statewide. Importantly, there is also limited teaching on and clinical exposure to clozapine in psychiatry residency training, leading to a dearth of experienced clinicians and administrators and further stigmatizing the use of clozapine. This course addresses the following: first, strategies to improve trainee exposure to and familiarity with clozapine in order to promote its appropriate use among early-career and other psychiatrists; second, approaches to disseminating evidence-based policies and practices including the use of clozapine (and complementary initiatives) within a large public mental health system; third, compatibility of clozapine with other recovery-oriented practices; and finally, we will review methods for 'crossing the quality chasm' between knowledge and practice through academic-public collaboration.

**This content was captured at the 2014 APA Annual Meeting


  • General Member - $12.50
  • Resident-Fellow Member - Free
  • Medical Student Member - $12.50
  • Non-Member - $25.00

Educational Objectives

  • Describe the rationale for using clozapine as part of recovery-oriented prescribing 
  • Determine site-specific barriers to clozapine use and list strategies to address barriers in public, academic, and community mental health settings 
  • Understand approaches to training early-career psychiatrists (ECPs) to use clozapine safely and appropriately 
  • Recognize ways to engage consumers, prescribers and administrators in shared decision-making involving clozapine 
  • Identify elements of initiatives to improve evidence-based clinical care in a public mental health system

Time to Complete

1 Hour

Target Audience

Resident/Fellows and Psychiatrists

How to Earn Credit

Participants who wish to earn AMA PRA Category 1 Credit ™ or a certificate of participation may do so by completing all sections of the course including the evaluation. A multiple choice quiz is provided based on the content. A passing score of 60% must be achieved. Retakes are available for the test. After evaluating the program, course participants will be provided with an opportunity to claim hours of participation and print an official CME certificate showing the date of completion and hours earned. 


The American Psychiatric Association (APA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The APA designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Faculty and Planner Disclosures


  • Cassis Henry, M.A., M.D., New York State Office of Mental Health, New York State Psychiatric Institute | Disclosure: Reports no financial relationships with commercial interests
  • Matthew D. Erlich, M.D., New York State Office of Mental Health, New York State Psychiatric Institute | Disclosure: Reports no financial relationships with commercial interests


  • Greg Miller, M.D., M.B.A., New York State Office of Mental Health | Disclosure: Reports no financial relationships with commercial interests
  • Oliver Freudenreich, M.D., Massachusetts General Hospital | Disclosure: Reports no financial relationships with commercial interests
  • Scott Stroup, M.D., M.P.H., Columbia University College of Physicians & Surgeons | Disclosure: Reports no financial relationships with commercial interests

Program Planners:

  • Tristan Gorrindo, M.D., Director of Education, American Psychiatric Association | Disclsoure: Reports no financial relationships with commercial interests
  • Ricardo Juarez, Associate Director, Office of International Affairs, American Psychiatric Association | Disclosure: Reports no financial relationships with commercial interests

Hardware/Software Requirements

Hardware/Software Specifications: 
This internet-based CME activity is best experienced using Internet Explorer 8+, Mozilla Firefox 3+, Safari 4+. This Web site requires that JavaScript and session cookies be enabled. Certain activities may require additional software to view multimedia, presentation, or printable versions of the content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Adobe Acrobat, Microsoft PowerPoint, and Windows Media Player.

Optimal System Configuration:

Flash Player: Adobe Flash Player 10.1+ 
Browser: Firefox 3+, Internet Explorer 8.0+, Safari 4.0+, or Google Chrome 7.0+ 
Operating System: Windows XP+ or Mac OS X 10.4+ 
Internet Connection: 1 Mbps or higher

Minimum Requirements:
Windows PC:
500-MHz Pentium II; Windows XP or higher; 128 MB RAM; Video Card at least 64MB of video memory; Sound Card at least 16-bit; Macromedia Flash Player 10 or higher, audio playback with speakers for programs with video content; Firefox 1.1+, Internet Explorer 7.0+, Safari 1.0+, Google Chrome, or Opera
Mac OS X 10.3 or higher with latest updates installed; 1.83MHz Intel Core Duo or faster; RAM: 128MB or more; Video Card: at least 64MB of video memory; Sound Card: at least 16-bit

For assistance: Contact for questions about this course | Contact for technical assistance

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