Description
Bipolar Depression is a largely understudied area. Patients are frequently misdiagnosed as Major Depression Disorder, which leads to utilization of inappropriate treatments including antidepressant monotherapy. Recent studies have shown that Patients with bipolar disorder experienced longer periods in the depressed than in manic phase. Furthermore, episodes of depression are the most frequent cause of disability among patients with bipolar disorder. Polarity of the first episode has predictive value on long-term course of the condition, including the predominance of future episodes. Polarity of patients’ first reported mood episode suggests that depression-prone subtypes have a greater probability of suicidal acts. Patients with bipolar disorder who experienced a first episode of depression have a long-term predominant presentation of depressive episodes and subsyndromal depressive symptoms. Bipolar depression when accompanied by mixed features has higher risk of suicidal behavior and presence of comorbidity substance use disorder. Treatment resistant bipolar depression is highly prevalent. New pharmacological and Neuromodulation (e.g. ECT, TMS) treatments have improved the outcome of acute bipolar depression and the prevention of relapse to depression. Result from recent pharmacological treatments including Lurasidone, Cariprazine Lumateperone, and Ketamine; as well at those utilizing Neuromodulation approaches. Finally, the use of antidepressants in bipolar depression remains controversial, especially as monotherapy, however in combination with mood stabilizers or atypical antipsychotics they appear to be a treatment option. Risk factors for antidepressants causing emerging symptoms of mania have been identified.
Format
Recorded webinar, non-interactive, self-paced distance learning activity.
This presentation was recorded at the American Psychiatric Association Annual Meeting 2022.
Learning Objectives
- At the conclusion of this session, the participant will be able to identify risk factors of emergence of mixed symptoms with the use of antidepressants
- At the conclusion of this session, the participant will be able to identify the challenges and opportunities of the use of antidepressants in Bipolar Depression
- At the conclusion of this session, the participant will be able to identify the efficacy and tolerability of antipsychotics in the treatment of Bipolar Depression
- At the conclusion of this session, the participant will be able to identify the efficacy and tolerability of lithium and mood stabilizers in the treatment of Bipolar Depression
- At the conclusion of this session, the participant will be able to identify the challenges and opportunities of the use of Ketamine in Bipolar Depression
Target Audience
Psychiatrists
Estimated Time to Complete
Estimated Duration: 90 minutes
Begin Date: December 1, 2023
End Date: December 1, 2026
How to Earn Credit
Participants who wish to earn AMA PRA Category 1 Credit ™ or a certificate of participation may do so by completing all sections of the course including the evaluation. After evaluating the program, course participants will be provided with an opportunity to claim hours of participation and print an official CME certificate (physicians) or certificate of participation (non-physicians) showing the event date and hours earned.
Continuing Education Credit
In support of improving patient care, the American Psychiatric Association is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physicians
The APA designates this enduring activity for a maximum of 1.5 AMA PRA Category 1 Credit ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Faculty and Planner Disclosures
The American Psychiatric Association adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Medical Education. Any individuals in a position to control the content of a CME activity — including faculty, planners, reviewers or others — are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.
Program Presenters
- Mauricio Tohen, MD, DrPH, MBA. Reports no financial relationships with commercial interests.
- Leonardo Tondo, MD. Reports no financial relationships with commercial interests.
- Gustavo Vasquez, MD, PhD, FRCPC. Reports no financial relationships with commercial interests.
- Jair Soares, MD, PhD. Reports no financial relationships with commercial interests.
Program Planners
- Jacqueline Maus Feldman, M.D., Chairperson, Scientific Program Committee, Reports no financial relationships with commercial interests.
- Robert O. Cotes, M.D., Vice-Chairperson, Scientific Program Committee, Reports no financial relationships with commercial interests.
- Uchenna Okeye, M.D., Vice-Chairperson, Scientific Program Committee, Reports no financial relationships with commercial interests.
Accessibility for Participants with Disabilities
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Technical Requirements
This internet-based CME activity is best experienced using any of the following:
- The latest and 2nd latest public versions of Google Chrome, Mozilla Firefox, or Safari
- Internet Explorer 11+
This Web site requires that JavaScript and session cookies be enabled. Certain activities may require additional software to view multimedia, presentation, or printable versions of the content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Acrobat Reader, Microsoft PowerPoint, and Windows Media Player.
Optimal System Configuration:
- Browser: Google Chrome (latest and 2nd latest version), Safari (latest and 2nd latest version), Internet Explorer 11.0+, Firefox (latest and 2nd latest version), or Microsoft Edge (latest and 2nd latest version)
- Operating System: Windows versions 8.1+, Mac OS X 10.5 (Leopard) +, Android (latest and 2nd latest version), or iOS/iPad OS (latest and 2nd latest version)
- Internet Connection: 1 Mbps or higher
Minimum Requirements:
- Windows PC: Windows 8.1 or higher; 1 GB (for 32-bit)/2 GB (for 64-bit) or higher RAM; Microsoft DirectX 9 graphics device with WDDM driver; audio playback with speakers for programs with video content
- Macintosh: Mac OS X 10.5 or higher with latest updates installed; Intel, PowerPC G5, or PowerPC G4 (867MHz or faster) processor; 512 MB or higher RAM; audio playback with speakers for programs with video content
For assistance: Contact educme@psych.org for questions about this activity | Contact learningcenter@psych.org for technical assistance