Description
Clinical evidence base in bipolar disorder treatment has substantial gaps and precision medicine approaches to treatment based on genetic, environmental, and lifestyle factors has yet to be developed. A paradigm shift in patient centered research that supports a learning health system is needed. This symposium will review a proposed road map for this mandate highlighting the merits of clinical deep phenotyping in a learning health system. While now well recognized that treatment response and remission rates are inadequate to capture optimal functioning, the clinical factors contributing to impairment are not fully understood. As presented by Dr. Burdick, quantifying predictors of functional impairment would set a path to phenotype impairment as a target for future individualized therapeutic interventions. As reviewed by Dr. Frye, multiple studies examining neuroimaging, peripheral markers and genetics have provided important insights into the pathophysiologic processes underlying bipolar disorder. Further, pharmacogenomics and other biomarkers of drug response are of increasing clinical interest and have potential to individualize treatment recommendations with greater precision for individual patients based on their biology. As reviewed by Dr. Wang, Learning Health Systems (LHS) have been proposed as a tool for healthcare reform to address access, equity, and value of healthcare. Key components of an operational LHS include measurement- based patient-reported outcomes such as the PHQ-9, integration of outcome measures into an electronic health record (EHR), a machine-learnable digital knowledge base, a platform for applying clinical informatics and artificial intelligence to develop, test, and adapt innovations, and a work force that embraces learning through real-world care.
Format
Recorded webinar.
This content was recorded during the APA 2023 Annual Meeting.
Learning Objectives
- Appreciate how measuring and phenotyping functional impairment in bipolar disorder can inform risk models of relapse and interventions targeting impairment in clinical practice.
- Review the working definition of a validated biomarker (neuroimaging, genomic, peripheral) and appreciate how they can inform clinical decision making in bipolar disorder treatment.
- Examine the tenets of a learning health system that can leverage patient-reported mental health symptoms and substance use data and, by providing a platform for real time data analytics.
Target Audience
Residents/Fellows, Psychiatrists, Psychologists
Estimate Time to Complete
Estimated Duration: 1.5 hours
Program Start Date: May 1, 2025
Program End Date: May 1, 2028
How to Earn Credit
Participants who wish to earn AMA PRA Category 1 Credit™ may do so after completing all sections of the course including the evaluation. After evaluating the program, course participants will be provided with an opportunity to claim hours of participation and print an official CME certificate (physicians) or certificate of participation (non-physicians) showing the completion date and hours earned.
Continuing Education Credit
In support of improving patient care, the American Psychiatric Association is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
The APA designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Faculty and Planner Disclosures
The American Psychiatric Association adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Medical Education. Any individuals in a position to control the content of a CME activity — including faculty, planners, reviewers or others — are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.
Instructors
- Mark Frye, MD
- Katherine Burdick, MD
- Philip Wang, MD
Planners
- Vishal Madaan, MD, Chief of Education and Deputy Medical Director at the American Psychiatric Association.
Accessibility for Participants with Disabilities
The American Psychiatric Association is committed to ensuring accessibility of its website to people with disabilities. Please contact the American Psychiatric Association at 202-559-3900, if you require assistance seven (7) business days prior to the start of a live webinar.
Technical Requirements
This internet-based CME activity is best experienced using any of the following:
- The latest and 2nd latest public versions of Google Chrome, Mozilla Firefox, or Safari
- Internet Explorer 11+
This Web site requires that JavaScript and session cookies be enabled. Certain activities may require additional software to view multimedia, presentation, or printable versions of the content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Acrobat Reader, Microsoft PowerPoint, and Windows Media Player.
Optimal System Configuration:
- Browser: Google Chrome (latest and 2nd latest version), Safari (latest and 2nd latest version), Internet Explorer 11.0+, Firefox (latest and 2nd latest version), or Microsoft Edge (latest and 2nd latest version)
- Operating System: Windows versions 8.1+, Mac OS X 10.5 (Leopard) +, Android (latest and 2nd latest version), or iOS/iPad OS (latest and 2nd latest version)
- Internet Connection: 1 Mbps or higher
Minimum Requirements:
- Windows PC: Windows 8.1 or higher; 1 GB (for 32-bit)/2 GB (for 64-bit) or higher RAM; Microsoft DirectX 9 graphics device with WDDM driver; audio playback with speakers for programs with video content
- Macintosh: Mac OS X 10.5 or higher with latest updates installed; Intel, PowerPC G5, or PowerPC G4 (867MHz or faster) processor; 512 MB or higher RAM; audio playback with speakers for programs with video content
For assistance: Contact educme@psych.org for questions about this activity | Contact learningcenter@psych.org for technical assistance