Treatment as Prevention: Improving the Outcome of Schizophrenia-View Presentation Slides

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The document provides detailed insights into various aspects of schizophrenia care, focusing on preemptive and proactive treatment strategies to improve patient outcomes. It highlights a stage-based approach to schizophrenia treatment, emphasizing early intervention and the use of stage-specific care to tailor interventions. Key treatment strategies discussed include the utilization of long-acting injectable antipsychotics (LAIs) over oral ones for better adherence and the pivotal role of clozapine in treatment-resistant schizophrenia (TRS).<br /><br />Clozapine is specifically noted for its efficacy in addressing treatment resistance and associated complications like suicidality and aggression, although it is often underutilized. The presentation stresses the importance of early and routine use of clozapine, rather than reserving it as a last resort. There's also an emphasis on reducing the Duration of Untreated Psychosis (DUP) to improve cognitive outcomes over time.<br /><br />Further, the document explores the broader intersection of mental and physical health, addressing the need for proactive medical management, especially concerning antipsychotic-induced weight gain. Emerging treatments like GLP-1 agonists are discussed for their potential in managing this weight gain. The presentation also underscores the significance of addressing smoking and ensuring vaccination in patients with serious mental illnesses to reduce medical mortality.<br /><br />Inclusion of social interventions and the coordination of care within community settings, along with the appropriate use of pharmacotherapy, are highlighted as crucial components. Finally, the document touches on broader issues such as the role of professionals in societal changes and climate action, advocating for holistic care that includes the well-being of patients in the context of environmental and societal health.

Keywords

schizophrenia care

preemptive treatment

stage-based approach

long-acting injectable antipsychotics

clozapine

treatment-resistant schizophrenia

Duration of Untreated Psychosis

GLP-1 agonists

social interventions

holistic care