Office-Based Buprenorphine Treatment of Opioid Use Disorder (Online)-Module 2: View Lecture (Overview of EX-Naltrexone, Methadone, and Naloxone)

Video Transcription

Video Summary

In this video transcript, the speaker discusses various topics related to opioid addiction and treatment. The first topic covered is extended-release naltrexone, which is a long-acting opioid receptor antagonist used to prevent relapse and opiate use. The speaker explains that the medication works by blocking all opioid effects, thus preventing the individual from experiencing an opiate high. The extended-release formulation of naltrexone is the main focus of the discussion, as it has been approved for the prevention of relapse and opiate use. However, there are some limitations to this treatment, including the logistics of beginning the treatment and the difficulty for patients to avoid opiate use during the required withdrawal period. The speaker also mentions that there are still many unknowns about naltrexone, such as the ideal duration of treatment and the best dosing frequency. <br /><br />The second topic briefly discussed is methadone, another medication used for the treatment of opioid addiction. The speaker explains that methadone can stabilize lifestyle, improve health, reduce criminal behavior, and increase employment. However, there are some side effects and risks associated with methadone treatment, such as sedation, constipation, and the potential for prolonged QTC intervals in susceptible individuals. The speaker also mentions the importance of monitoring drug interactions with methadone.<br /><br />The last topic covered is naloxone, an opioid antagonist used to treat opioid overdose. The speaker explains that naloxone works by blocking opioid receptors and preventing opioids from reaching the brain. The speaker provides instructions on how to recognize an opioid overdose, administer naloxone, and respond to an overdose situation. It is emphasized that naloxone treatment should be followed by counseling or addiction treatment.<br /><br />Overall, the video transcript discusses extended-release naltrexone, methadone, and naloxone as treatment options for opioid addiction, highlighting their effectiveness, limitations, and associated risks.

Keywords

opioid addiction

treatment

extended-release naltrexone

opiate use

methadone

naloxone

overdose