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Lifelong Learning: Lithium Exposure During Pregnan ...
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A systematic review and meta-analysis found that lithium exposure during pregnancy is associated with a higher risk of spontaneous abortion, congenital anomalies, and cardiac anomalies. However, it did not increase the risk of preterm birth or low birth weight. Lithium was effective in preventing postpartum mood episodes. The dosage and serum lithium levels during pregnancy affected fetal and newborn outcomes, with higher dosages being associated with a higher risk of cardiac malformations. The study recommends careful consideration of the benefits and risks of using lithium during pregnancy on a case-by-case basis, with close monitoring of lithium levels.
Keywords
lithium exposure
pregnancy
spontaneous abortion
congenital anomalies
cardiac anomalies
preterm birth
low birth weight
postpartum mood episodes
dosage
serum lithium levels
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