Early Intervention in Psychotic Disorders - Where Are We and Where Are We Going?-View Recording

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Video Summary

Dr. Dost Angur, a prominent figure in the field of psychotic disorders, delivered a lecture detailing the landscape of early intervention strategies in psychotic disorders, highlighting his extensive responsibilities and research efforts. As Chief of Division of Psychotic Disorders, Dr. Angur oversees multiple clinical and research facilities with a focus on improving patient outcomes. His work, aided by funding from institutions like the National Institutes of Mental Health, centers on schizophrenia and bipolar disorder's neurobiology and clinical manifestations.<br /><br />Dr. Angur emphasized the importance of early intervention in psychotic disorders, aligning with the philosophy that these disorders represent a critical window of opportunity for intervention to prevent long-term disability. Rather than viewing the onset of these disorders as an irreversible decline, early intervention aims to alter the trajectory towards recovery.<br /><br />Coordinated Specialty Care (CSC) is advocated as the standard of care for early intervention, featuring team-based, person-centered, and phase-specific treatments. Dr. Angur discussed the implementation and efficacy of CSC, citing studies like the RAISE project that demonstrated superior outcomes compared to routine care. Acknowledging the challenges, he highlighted efforts to improve accessibility, reduce clinician burnout, and integrate primary prevention strategies, such as public health messaging on cannabis use, to curb early onset of disorders.<br /><br />In the field of research, Dr. Angur elaborated on investigating neurobiological aspects, specifically brain energy metabolism, through techniques like Phosphorus MRS, revealing significant abnormalities in energy production in patients with psychotic disorders. This research opens potential therapeutic avenues with interventions like ketogenic diets showing promise.<br /><br />Overall, Dr. Angur’s talk underscored the need for an integrated and proactive approach to managing psychotic disorders, combining clinical care advancements with ongoing research to improve long-term patient outcomes.

Keywords

psychotic disorders

early intervention

schizophrenia

bipolar disorder

neurobiology

Coordinated Specialty Care

RAISE project

brain energy metabolism

Phosphorus MRS

ketogenic diets

Dr. Dost Angur

National Institutes of Mental Health

patient outcomes