Delirium - @the APA-Delirium Updates Slides

Delirium Updates Slides

Pdf Summary

Dr. Jose R. Maldonado, a leading expert in Psychiatry and Critical Care at Stanford University, addresses the complexities of delirium and its management through a comprehensive exploration of factors, hypotheses, and strategies. His research emphasizes the significance of early detection, risk assessment, and understanding the underlying mechanisms of delirium for effective treatment. Various topics covered include the relationship between delirium and encephalopathy, the impact of neuroendocrine dysregulation and oxidative stress, and the implications of circadian dysregulation and oxidative stress on cognitive function. Dr. Maldonado's work also delves into the connections between delirium and dementia, underscoring the acceleration of cognitive decline and heightened dementia risk in older adults experiencing delirium.<br /><br />In addition to pharmacological approaches utilizing medications like dexmedetomidine and antipsychotics to manage delirium, the document also highlights the importance of non-pharmacological interventions such as early mobilization and family involvement in preventing and treating delirium. Dr. Maldonado's research findings showcase the efficacy of various medications in reducing delirium severity and duration while emphasizing careful selection and monitoring to minimize adverse effects.<br /><br />Furthermore, the document discusses the management of alcohol withdrawal syndromes (AWS) by Dr. Maldonado, detailing the efficacy of pharmacological interventions like antipsychotics and anticonvulsants alongside non-pharmacological techniques. It also introduces tools like the Prediction of Alcohol Withdrawal Assessment Scale (PAWSS) and Stanford's BDZP-sparing protocol for AWS management. Through evidence-based protocols and a multidisciplinary approach, Dr. Maldonado aims to enhance patient care and outcomes in addressing delirium and AWS, ultimately contributing to advancements in understanding and treating these conditions with a focus on patient safety and holistic care.

Keywords

Dr. Jose R. Maldonado

Psychiatry

Critical Care

Delirium Management

Risk Assessment

Neuroendocrine Dysregulation

Oxidative Stress

Circadian Dysregulation

Dementia

Alcohol Withdrawal Syndromes