Abstract: Deep brain stimulation (DBS) is an effective treatment for motor symptoms in advanced Parkinson’s disease. Most commonly, DBS electrodes are placed in the subthalamic nucleus (STN) but can also be placed in the globus pallidus pars interna. The STN comprises three main functional subterritories. The dorsolateral region is the motor territory, the ventromedial portion is the associative territory, and the anteromedial region subserves limbic function.
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The participant will recognize potential contributing factors to adverse behavioral effects associated with deep brain stimulation for Parkinson’s disease.
This program is designed for all psychiatrists in clinical practice, residents in Graduate Medical Education programs, medical students interested in psychiatry, and other physicians who wish to advance their current knowledge of clinical medicine.
Duration: 1 hour
Begin Date: January 1, 2017
End Date: December 31, 2018
In order to earn CME credit, subscribers should read through the material presented in the article. After reading the article, complete the quiz and submit your evaluation and study hours (up to 1 AMA PRA Category 1 Credit™). A score of 60% or higher is required to receive credit.
The American Psychiatric Association (APA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
The APA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Title: Disambiguating the Psychiatric Sequelae of Parkinson’s Disease, Deep Brain Stimulation, and Life Events: Case Report and Literature Review
Authors: Rachel A. Davis, M.D., Christen H. Epstein, N.P., Olga Klepitskaya, M.D., Christopher S. Sharp, M.D., Steven Ojemann, M.D., Aviva Abosch, M.D., Ph.D., Alison M. Heru, M.D.
Affiliations: From the Departments of Psychiatry, Neurology, and Neurosurgery, University of Colorado Anschutz Medical Campus, Aurora (R.A.D., C.H.E., O.K., C.S.S., S.O., A.A., A.M.H.).
Disclosures: Dr. Klepitskaya has served as a consultant for Acadia Pharmaceuticals and Cynapsus Therapeutics and is conducting clinical trials for U.S. WorldMeds. Dr. Ojemann has served as a consultant for Medtronic and as a data safety monitoring board member for Voyager Therapeutics. Dr. Abosch has served as a consultant for Medtronic. The other authors report no financial relationships with commercial interests.
Discussion of unapproved or investigational use of products*: No.
*APA policy requires disclosure by CME authors of unapproved or investigational use of products discussed in CME programs. Off-label use of medications by individual physicians is permitted and common. Decisions about off-label use can be guided by scientific literature and clinical experience.
Robert Freedman, M.D. (Editor-in-Chief, AJP); Susan K. Schultz, M.D. (Deputy Editor, AJP); Michael D. Roy (Editorial Director, AJP); Michael A. Pogachar (Online Content Manager, Journals).
Dr. Schultz has received research support from the Alzheimer’s Disease Cooperative Study for projects conducted in partnership with Toyama Chemical Company and in partnership with Eli Lilly and Company. Dr. Freedman, Mr. Roy, and Mr. Pogachar report no financial relationships with commercial interests.
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